Once the game begins, your two commanders are tracked separately. If you cast one, you won't have to pay an additional {2} the first time you cast the other. A player loses the game after having been dealt 21 damage from any one of them, not from both of them combined.
Radiant, Serra Archangel
An effect that checks whether you control your commander is satisfied if you control one or both of your two commanders.
If something refers to your commander while you have two commanders, it refers to one of them of your choice. If you are instructed to perform an action on your commander (e.g. put it from the command zone into your hand due to Command Beacon), you choose one of your commanders at the time the effect happens.
Magic: The Gathering · ™ & © Wizards of the Coast · Illus. Chris Rallis
Card data via Scryfall. Rarix is fan-made; not endorsed by the rights holders.
